off-target effect 脫靶效應

off-target effect
繁：脫靶效應
简：脱靶效应

但他指現時該技術的安全性尚待解決，包括先以動物作實驗評估、編輯基因後出現的「脫靶效應」、嵌合體發生、可能影響胚胎發育及多代繁殖後是否健康等五大問題。

賀建奎曾言：基因改造涉五安全隱憂（2018年11月28日）。東網，取自 https://hk.on.cc/hk/bkn/cnt/news/20181128/bkn-20181128033038901-1128_00822_001.html

This is called “off-target effects.”

Flawed DNA editing of alleged ‘designer babies’ may have put their health at risk. (2018, November 29). The Verge. Retrieved from https://www.theverge.com/2018/11/29/18116830/crispr-baby-he-jiankui-genetics-ethics-science-health-mutation